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Cocktails, tablets, capsules, and individual purified formulations of protease inhibitors and phosphatase inhibitors designed to protect proteins from degradation during cell lysis and extraction.
The VEGFR2 Kinase Inhibitor III, also referenced under CAS 204005-46-9, controls the biological activity of VEGFR2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
A cell-permeable pyridinyloxypyridine compound that acts as a potent and highly selective inhibitor against TGFβ RI/ALK5 (IC50 = 72 nM, [ATP] = 1 mM) by targeting both the ATP-binding site and the selectivity pocket, while exhibiting much reduced or little activity against a panel of 75 other kinases (IC50 <1μM).
Isogranulatimide, also referenced under CAS 244148-46-7, modulates the biological activity of Chk1 and GSK-3β. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
The Wee1/Chk1 Inhibitor, also referenced under CAS 1177150-89-8, controls the biological activity of Wee1/Chk1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Rapamycin, CAS 53123-88-9, is an immunosuppressant that selectively inhibits mTOR and blocks the subsequent activation of p70 S6 kinase (IC50 = 50 pM).
The Caspase-4 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-4. This small molecule/inhibitor is primarily used for Cancer applications.
The Plasminogen Activator Inhibitor-1, Mutant, Mouse, Recombinant controls the biological activity of Plasminogen Activator. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
The Serine/Threonine Kinase Inhibitor Set controls the biological activity of Serine/Threonine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
A cell-permeable benzothiazole compound that exhibits potent in vitro antiproliferative activity against HCC 2998, IGROV1, MCF-7, MDA 468, SR, and T-47D.
A cell-permeable compound that targets the conserved C-terminal domain of SPAK and OSR1 via reversible binding (Kd = 20 μM; rat SPAK-CCT452-553 GST fusion).